SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c16db288c70305740cb7361512f25fb99c12fc2678f405d8a29006254e5d204' 
  AND token = 'W6j8Id6jkYUdjLh87SeK/ykQ2G24pNw9DK1pyjocq7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}