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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fc1d95285a73d5a960673f5b96edc26628a1d0a1bbdb0edf3c1a0312f6a6846' 
  AND token = 'oW11YsJ19mjDcEJFTmjSZ6X31vAHCjApWOulzc6P5Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}