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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aff66c2070a773463fbc286186736122ddc8e7142774cbb9f2df17886561a45' 
  AND token = 'vItUzb2mFqNwdOq0HnuoTOhSKlU1xXWSADgL6zqz384=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}