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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7224fcdec5fe7ca37fe134cacec1d7fcaa609ce2b2bcc98dd9a57801a51acd5c' 
  AND token = 'NZYNiVuxsG/4DtKeap/TK4eBrMbD75qvT8wJxKqP0XE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}