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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fc9b5a8e4d641d33b8e0b0cb54d695de7571945c5e3e2890221aef00e339911' 
  AND token = 'jtspJf1Z+bfWfRPeBo385BK8kPoWl2SkRul5k3cH75Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}