SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d7cb1fc4869bc2ef54d2029319f6df0385c391efb7ae93b750de17f9937ed2' 
  AND token = 'RsSM3+ZltAXaiEJpuqTQnB3pHognAlsf4dMyEXO4IEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}