SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bb39116386ae7f9cf13b269a3bb122eaf25b89e3e12b349d8bef1424c75a2e8' 
  AND token = 'K5zh8XVeGdVBO+thNEAbPUIg0MjJt5cZdxIacSCooe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}