SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '393ff69d2a7e59c82a8675815aab6f21518d22f5c08ad0f4c092a7f3644ed65b' 
  AND token = 'L4RatRdUZUeTf6UpKshJWEGDFn4xf0Fj1odn2aM2R7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}