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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb76ba95fb4bfde7bfc8757866c9b066ae42d2b43aa95c11958746c24680ce0f' 
  AND token = '2BB0i1dFXBjBsrzeFHp5yEah/ULjGJ0mTUmIzjZaUcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}