SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7295ea5ab9019a108dfed2d2887763f96ef0a200e946dc80c9da79df72fbe636' 
  AND token = '43JXsxyI1M2yo4WWys0sRoa/7ugLLOoiX8ta+UKos6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}