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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd580e167d6ac68bdbf14c85b2970f1d085210c6e2a6f9c8428dc180c6ef0714f' 
  AND token = 'u61x9gcoEHQEo1j57umYpcr0V4hzZ7fCv+njFYaREEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}