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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '736613d1e2fb2714b89608378621f96125c5085ee10f7544b28e08a31f22d34b' 
  AND token = 'EMhv9TUwZCL/tomsxQpsw2hTDeOrPERh6Tws90B7ktQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}