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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0d18005a584476d222fc68bfbafab4dc2089f24529ff9831d93254e26f33ff5' 
  AND token = 'Qq/+jb4FUSUJW6izsTRTgOsHoWAa9bYrFxV3s2Ixylw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}