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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ddeecb14446d4940080ab6c1cd2f388443c9ab360f29007ef8855c03643e37a' 
  AND token = 'HYc6JlLQTC8R4m91NabxN0UXTx7HKxfzTE9fsd2r4d4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}