SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e1ac80717ca8d9ecedb035fb5265b39de084300f8c1473579331a4d08550000' 
  AND token = 'gKhz5laO7n1+Y5TCW7B+ELrASSl6fzSh+Yvj/OofQeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}