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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec4abdbe644f11c0f1473c5ad0e1de84ab06f83334fd0d2c4a7759f9d37984ae' 
  AND token = 'RGmhhkd/Entr0CNUKPqKqIv3G5FC1M2BWKVl5OlhB7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}