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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '050ad1930f9986b5a30a4e20d0d0dadfa6b3d23216ba28663ce23d77e0e64183' 
  AND token = 'Qo4eatNQCnu7W3XxQHRCBc2HbmmPn8A9A0ZEsEnUNck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}