SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bb061ceee179dc5a325f268e7348ba1e290d1c61be8df4bdd4cbb69f8e8f191' 
  AND token = 'XYnAStJUcRtMPoBTV3asmzsAQByQbUXtjspTgXAW9d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}