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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b204ce8d93b9d3e9389201c641681aff87426f142f38369bf694235eeafbe8e' 
  AND token = 'b6wKKWD6cRx8/oQtnJfeR+rltQZ+drzJBrHlxgDqmZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}