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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8651a2a1d28aca446bf10c2e535c9688dc9d8d2f37a2a01001b202efe00c558c' 
  AND token = 'AhBKpMPbmf3INOqcud/R93Xi2CulT2aSlrqwvmuv+8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}