SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dd6f25030392db7a818a01cf39b6759fb2955777335acca179d0bcc86dab1a6' 
  AND token = 'iQqPt9jxTPG1qWHMDLuTCfQJhIs4FyPMmth878xnDwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}