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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2e27cef477468be4cf2ebdfbd09080aa3bef510f07492194c002bf4e8ea9cd3' 
  AND token = 'lW8pjP9d4b54YEhv7hKuJIBILCObvHvGvIWyOP5RnIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}