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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9b9bc3808dff2b9ca2e96b4e8cd0eac20795f02686c7dd65092183490cea3f8' 
  AND token = 'GCBhESWkGRb8peq7ui+AjAibKY1XXC79hwjhkMXlkfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}