SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc9af56e62f10ad40e2d5e532986494b90ba99e0dc8772d3211b41f468780293' 
  AND token = 'FP+u1OhaSQmuE/C9ONKvWiLBHC8rLe7RAANl3XNl0QE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}