SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5db151b262a8e77fa9384d35f48fa0bc851c4668cead53e0369c369611ee9306' 
  AND token = 'wsvz62vtu1LLTEP3Q0uZBveHmD0DoiZEVE0Pm3TbzJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}