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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f2e9008552d8da49329478dde90005ed5f505cb48446e9f90db5c5a128a80f' 
  AND token = 'o3krQIVUrqN7+eE+BgHqPYK8UNbLssnRggGfA4eZU/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}