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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ea00c20cb2883cfea63c9146ca9dadc102e9901c3cffea1e3f252b43d1ba5c4' 
  AND token = 'LiVdXrih4j8zJCWqU/sSfD7w7MSn7gUsSNpTzRJ2NLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}