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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6e491350815f82eb00040dff9a28305de8d755bca92c2f44b47e34f5cd3dd48' 
  AND token = 'pZa+s+ky5rCtZfPQoptpok8iqk0rWvn2CwdFNzMAc9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}