SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16a32a7f89316bfc8ccf2c522da3e34f2b1b694cdb690ad3c617cfcc7eb8d50b' 
  AND token = 'I5R3j9tt4n/vapvEb0GAGDB8nQhMq0ZJw1t309vCh5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}