SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71fb6be48f5d250a8e03b2c3402ab9e19b77c76584665d8bea1b4262666af981' 
  AND token = 'f2hTLVQ6aGwtNiW/lllssL3wM1GdUeA4qH4sFHDoJr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}