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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb6b23e608a6438ff6a6713b9233fb7a9a15df1338fce003d1b48396cbcc981c' 
  AND token = '8HTiuhg5h7YKlwMYOsaLkccNFPHIOjWAsqJfY9zOnlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}