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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4229fb558bc06b4ade6ceb454b0d46756ac3b7955c128b50ceae39c83686f0b5' 
  AND token = 'qSd1A5RUyMrJ3p8ylPolLQKnFS2EP+uZQCH+PKUr+gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}