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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b68c2966c261a78a2e26add1dfea421b66f1fcd6f7952b3ef4d4c36778a672c8' 
  AND token = 'pGipWtQhJAab4+lGADRuOURgsp8KEacLLbTt381MHEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}