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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d43f80c2ec7182ef007d78d8f21e351b9d624306570ba7d992bc3aabc997206' 
  AND token = '5VO2Ya8B0O4uvoJ8lT+WNBXGxbhej5xf3F45CUokd9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}