SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7577954772c1b1200ef0cb16fafad4f531e95c55eeaa22bbd282dda157e8c0d' 
  AND token = 'Z6ZQ3sv3Xxf4f2hUfgMF/cPsCmBxuzdOw3KIV0LsZO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}