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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c738a2a16172726ae636f7d26876022ae578e1a5bc7254714cffcebea2816c6' 
  AND token = 'GR0GkiG3Fh538KVfC54pW9qbvU9oOUmSm5bFfi3vUr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}