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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c5520f131c63e826156d55c463b554edb4f443a0535d3a8c0f5f9240ec2231' 
  AND token = 'U4uOQfHM67NdpDq7sdmtzqD0QRHSr6dLB/manyfpYiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}