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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fec6bc566f10a2366a5a9f2e47b4c1f779bb2138bab4e98fada5b9018fea8ac1' 
  AND token = 'oAEUuVTN3aT2noB0+TNg7i6OhRSTn7zSyCH1Aa2MLWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}