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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70b080cd25431f780118b943f830a83e8c524e1342d743c17302eb6d94097cca' 
  AND token = 'JC6JoaJygxUY21qrjCoWbjazZgTL4NmWtWF7fqsf3Jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}