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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41986d663b33b239802bef2629358faad2e4d35ec379ecc2d3da90c197fafc7c' 
  AND token = 'isBGPs3z792QtwE/s4fkGvfmPZ0/I9ym4spr9pf3Yk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}