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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f514463bae0399e80e235fa2f490f6c075b6cb1d2afcbfdcf8a1273130fb6a3d' 
  AND token = 'ynM9fWuDW0M3K6XhCkzcqaqoWwE/UjFzgMArPBOPZOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}