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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb3bd5b85f47de8364d249f5bf64ba20401eb19c4972b1523021821a257ab1e4' 
  AND token = 'Lw/9D72XOaxwLNLeyXFTC9mQFSSDeYEPEAKbP/0AaZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}