SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f0ba50af3bd2d0280b5df7e23253eac19a8d822bf626d80052a3548098eca34' 
  AND token = 'uL0pA/DdDmQz4Qqh4wpvzd22JkHNpB1WqQKdCt/tEII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}