SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53865c6bc08a2fc350351f63cb0295d8f493411885b877dca2a38279cb187247' 
  AND token = 'jarF7NIMR6wQbUYE5fqo338SM+53SqLOoqrRURn1fsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}