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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef36b41267562a51460877dc427fd9c9cdbc9a6e540382e2eedaf45019a745a9' 
  AND token = 'FgWnugvKmJPgdJDg1amVNGUS3gG42NR80DzEtJ1Z8ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}