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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4e5c5581211e41aee00a3c1909f817adcece9cd19a4e14b5e937b4accc65af2' 
  AND token = 'qZE8lJubR7OpPB9eucBSuoQoLH+Iz4PO5cVY7zaUw5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}