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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a7d9b1c6356b04aeff2d35ebd2f570bcc826ac5178041a1cc70291543d5018d' 
  AND token = 'rXMVBuxoiKJwRMudhgyuhWR8oJhkgN/H0T8c5HB1qn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}