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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f32c0f24abbaa5d8f0c00bc855620aa737fe53e1c2db64a1304f821e037fc5' 
  AND token = 'ZsIjf42SNDK8Ow5GSgAKYnsv0ZbOdm1VXaHbli/XTzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}