SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e9e6340547a1886e85a6ff3b1120bd08a80aa7b53ceead24bc55cc50cf927f' 
  AND token = 'jg3ldIWN0UUahBF3g/hayQZAeqOzzRByVXIC4GWZRwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}