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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee5f15fe871caaa1484584035f752a514eff282c3cdc0fcd9dc8037f9e49fdd2' 
  AND token = '/1piQp6rTK2UwEE+ebb2i3zbEGER1DG58ZgAlj9AHSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}